| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A recombinant partial protein sequence (within amino acids 395-595) from the human protein was used as the immunogen for the SHP-1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
SHP-1 Antibody / PTPN6 / PTP1C is an antibody targeting SHP-1. Host: Mouse. Monoclonal. Clone: PTPN6/7544. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: SHP-1.
- Immunogen: A recombinant partial protein sequence (within amino acids 395-595) from the human protein was used as the immunogen fo….
- Species reactivity: Human.
- Localization: Cytoplasm, Nucleus.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
PTPN6, which is also designated as SHP-1 and PTP1C, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
