SNS-032

SKU:BHB20430500
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Overview
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SNS-032 (CAS 345627-80-7) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 345627-80-7
Molecular Weight 380.53
Form Solid
Shipping Room Temperature
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Options selector
Catalog no. Size
T6049-5MG 5 mg
T6049-1MLX10MM 1 mL x 10 mM (in DMSO)
T6049-10MG 10 mg
T6049-25MG 25 mg
T6049-50MG 50 mg
T6049-100MG 100 mg
T6049-200MG 200 mg
T6049-500MG 500 mg
Field Specification
Activity
  • Kinase Inhibitor
Alternative Names SNS032
Cas No. 345627-80-7
Molecular Weight 380.53
Product Type
  • Small Molecule Inhibitor
Signaling Pathway PI3K/Akt/mTOR signaling///Cell Cycle/Checkpoint///Stem Cells///Apoptosis
SMILES C(SC=1SC(NC(=O)C2CCNCC2)=NC1)C=3OC(C(C)(C)C)=CN3
Target Apoptosis///GSK-3///CDK

Compound Overview

SNS-032 (CAS 345627-80-7) is a research-grade small molecule supplied by TargetMol.

Alternative names: SNS032

Physical Properties

CAS Number 345627-80-7
Molecular Formula C17H24N4O2S2
Molecular Weight 380.53 g/mol
SMILES C(SC=1SC(NC(=O)C2CCNCC2)=NC1)C=3OC(C(C)(C)C)=CN3
Form Solid
Shipping Room Temperature (RT)

Biological Activity

SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.

Target(s): Apoptosis, GSK-3, CDK

Signaling pathway(s): PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells, Apoptosis

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does prolonged sonication affect the compound structure?

It is recommended to sonicate at a lower frequency

What should I do if I find that the ice pack has melted upon receiving the product?

Melted ice packs are generally not a concern for solid powder compounds, as the short transit period at ambient temperature does not typically affect compound integrity or potency. Powder form is inherently more stable than solution form during temperature fluctuations. Upon receipt, transfer the compound to −20 °C immediately. If you observe color change, odor, or physical changes, contact BioHippo for quality investigation.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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