| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | E.coli-derived human SORLA/SORL1 recombinant protein (Position: D282-K708) was used as the immunogen for the SORL1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
SORL1 Antibody / Sortilin-related receptor / SORLA is an antibody targeting SORL1. Host: Rabbit. Polyclonal. Format: Lyophilized. Applications: WB, IHC, IF, FACS, ELISA.
Key elements and design rationale
- Target: SORL1.
- Immunogen: E.coli-derived human SORLA/SORL1 recombinant protein (Position: D282-K708) was used as the immunogen for the SORL1 anti….
- Species reactivity: Human, Mouse, Rat.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
SORL1 antibody detects Sortilin-related receptor, encoded by the SORL1 gene on chromosome 11q23.3. SORL1 antibody is widely used in research on protein trafficking, Alzheimer's disease, and neurodegeneration. Also known as SORLA, SORL1 belongs to the VPS10 domain receptor family, which regulates intracellular sorting of cargo proteins.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IHC: tissue distribution assessment; interpret with matched controls.
- IF/ICC: subcellular localization imaging with proper background controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
