Spike S1 Neutralizing Antibody (VHH), Fc-fusion (IgG1), Avi-Tag (SARS-CoV-1)

SKU:BHA18200019
Research Validated
Overview
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Anti-SARS-CoV-1 Spike S1 antibody (Human, Monoclonal, IgG1). Suitable for ELISA.
Clonality Monoclonal
Host Human
Reactivity SARS-CoV-1
Isotype IgG1
Applications ELISA
Options selector
Catalog no. Size
100784 100 ug
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 100 ug
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: Aqueous buffer solution.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No 100784
Clonality
  • Monoclonal
Conjugate
  • Unconjugated
Formulation 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Host Human
Isotype
  • IgG1
Molecular Weight 43 kDa
Product Type
  • Nanobody
Reactivity
  • SARS-CoV-1
Shipping -80°C (dry ice)
Species SARS-CoV-1
Storage Aqueous buffer solution.
Target SARS-CoV-1 Spike S1

Coronavirus

Product Overview

SARS-CoV monoclonal Spike S1 VHH neutralizing antibody, a.a. 1-127(full length), with C-terminal Avi-Tag™ fused to the Fc portion of Human IgG1, expressed in a HEK293 cell expression system. MW = 43 kDa. VHHs are single-domain antibodies from camelids.

Clonality Monoclonal
Host Human
Antibody Type IgG1
Isotype IgG1
Tag/Label C-terminal Fc-Avi-Tag
Reactivity SARS-CoV-1
Purification Protein A chromatography
Molecular Weight 43 kDa
Amino Acids 1-127(full length)
Formulation 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Storage Aqueous buffer solution.

Validated Applications

  • ELISA

Assay conditions: Inhibition of ACE2:SARS-CoV-1 Spike binding by a small anti-SARS-CoV-1 Spike antibody, VHH (BPS Bioscience, #100784). A small anti-SARS-CoV-1 Spike antibody was evaluated using the SARS-CoV-1 Spike Trimer (S1+S2):ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience, #79999). The antibody was serially diluted in 1x Immuno Buffer (BPS Bioscience, #79311) and tested following the assay kit protocol.

Immunogen / Antigen Information

Immunogen information not provided. Please refer to the product datasheet for detailed antigen information.

Cross-Reactivity & Specificity

Cross-reactivity data: Species reactivity as listed. No additional cross-reactivity data is available from the manufacturer.

Safety & Handling

Biosafety Level: Not applicable (BSL-1)

Avoid freeze/thaw cycles.

For Research Use Only (RUO). Not for diagnostic, therapeutic, or clinical use. Handle with standard laboratory precautions (gloves, safety glasses, lab coat). Avoid freeze-thaw cycles. Consult SDS prior to use.

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What applications have been validated for this SARS-CoV-1 Spike S1 antibody?

This antibody has been validated for: ELISA. Optimal dilutions and concentrations should be empirically determined for each specific application and sample type. Refer to the product datasheet for suggested starting conditions.

What is the recommended storage and handling protocol?

This antibody should be stored at the indicated temperature to maintain stability. Store at Aqueous buffer solution.. Avoid repeated freeze-thaw cycles, which can reduce antibody performance and increase aggregation. Centrifuge briefly after thawing and keep on ice during use.

What is the immunogen used to generate this SARS-CoV-1 Spike S1 antibody?

Please refer to the BPS Bioscience datasheet for detailed immunogen information.

Does this antibody cross-react with SARS-CoV-1 Spike S1 from other species?

Cross-reactivity data is limited; refer to the product datasheet for available information.

Is a conjugate or labeled format available for this antibody?

BPS Bioscience offers multiple antibody formats for key checkpoint and immunotherapy targets. Contact BioHippo (support@biohippo.com) or click "Talk to a Scientist" to inquire about additional conjugate formats, bulk quantities, or custom formulations.

Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

  1. Ho, M. et al., Antibody Therapeutics. 2020; 3(2): 109-114
  2. Wrapp, D. et al., 2020. Cell 181: 1004-1015

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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