| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | SPM 242 |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
SPM-242 is a research-grade small molecule supplied by TargetMol.
Alternative names: SPM 242
Physical Properties
| Molecular Formula | C16H19ClNO6PS |
|---|---|
| Molecular Weight | 419.81 g/mol |
| SMILES | OC1=CC=CC(SC2=CC=C(CC(C)(CO)(OP(O)(O)=O)N)C(Cl)=C2)=C1 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
SPM-242 is an orthosteric agonist of Sphingosine 1-phosphate (S1P) and a bitopic antagonist. S1P is a lysophospholipid signaling molecule that regulates important biological functions, including vascular development and lymphocyte trafficking, by activating G protein-coupled receptors for S1P, namely, S1P(1) through S1P(5).
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Tween-20 is not recommended. Tween-80 has better tolerance and has been used as a tool to assess the behavioral effects of experimental drugs and toxins without significant side effects. Reference: Castro CA, Hogan JB, Benson KA, Shehata CW, Landauer MR. Behavioral effects of vehicles: DMSO, ethanol, Tween-20, Tween-80, and emulphor-620. Pharmacol Biochem Behav. 1995 Apr;50(4):521-6.
For small packages(1 mg, 5 mg, 10 mg, etc.）, it is not recommended to weigh them again which may lead to compound loss and inaccurate measurement. Our products are imported in their original packaging and accurately weighed, so you can directly dissolve the compound in the appropriate solvent upon receipt. For large packages, you can weigh and prepare stock solutions. It is recommended to start with at least 10 mg to reduce error. If conditions permit, you can first prepare a high-concentration stock solution and then aliquot it for use
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
