| Field | Specification |
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| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human TAOK1 was used as the immunogen for the TAOK1 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
TAOK1 Antibody / Thousand and one amino acid protein kinase 1 is a anti-TAOK1 Rabbit antibody Recombinant Rabbit Monoclonal clone 30T29 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human, Mouse, Rat.
Key elements and design rationale
- Target: TAOK1
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 30T29, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB
Biological background
TAOK1 antibody is widely used in studies of kinase signaling, neuronal development, and cancer biology. In neurons, TAOK1 has been linked to axon outgrowth, dendritic branching, and synaptic plasticity. Mutations and altered expression of TAOK1 have been implicated in neurodevelopmental disorders including autism spectrum disorder. By detecting TAOK1, researchers can evaluate how changes in kinase signaling contribute to brain development and function.
The antibody is suitable for western blotting, immunohistochemistry, and immunofluorescence. Western blot assays detect bands corresponding to TAOK1 isoforms across different tissues. Immunohistochemistry highlights expression in developing brain regions, while immunofluorescence provides subcellular localization at cytoskeletal structures and kinases in signaling complexes.
TAOK1 also regulates apoptotic pathways through activation of stress activated protein kinases. It contributes to programmed cell death under stress conditions, linking it to cancer and degenerative disease. Elevated TAOK1 expression has been reported in tumors, where it may affect proliferation and survival pathways. By applying TAOK1 antibody, scientists can study its role in balancing survival and death signals in health and disease.
TAOK1 antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
