| Field | Specification |
|---|---|
| Target | |
| Alternative names | Terminal nucleotidyltransferase 4B|Non-canonical poly(A) RNA polymerase PAPD5|PAP-associated domain-containing protein 5|Terminal guanylyltransferase|Terminal uridylyltransferase 3 (TUTase 3)|Topoisomerase-related function protein 4-2 (TRF4-2)|TENT4B|GLD4|PAPD5|TRF4-2|TUT3 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | PAP associated domain containing 5 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes TENT4B. It is validated for ELISA, Western Blot, Immunoprecipitation.
Validated Applications
| Applications | ELISA, Western Blot, Immunoprecipitation |
|---|---|
| WB | 1:500 - 1:2000 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
PAP associated domain containing 5
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | PAP associated domain containing 5 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 50 kDa, 80 kDa |
| UniProt # | Q8NDF8 |
| Gene ID | 64282 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Terminal nucleotidyltransferase 4B|Non-canonical poly(A) RNA polymerase PAPD5|PAP-associated domain-containing protein 5|Terminal guanylyltransferase|Terminal uridylyltransferase 3 (TUTase 3)|Topoisomerase-related function protein 4-2 (TRF4-2)|TENT4B|GLD4|PAPD5|TRF4-2|TUT3 |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for TENT4B research from Fine Test, or contact us for alternative formats.
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