| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 3,3',5-Triiodothyroacetic acid |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Tiratricol (CAS 51-24-1) is a research-grade small molecule supplied by TargetMol.
Alternative names: 3,3',5-Triiodothyroacetic acid
Physical Properties
| CAS Number | 51-24-1 |
|---|---|
| Molecular Formula | C14H9I3O4 |
| Molecular Weight | 621.93 g/mol |
| SMILES | O(C1=C(I)C=C(CC(O)=O)C=C1I)C2=CC(I)=C(O)C=C2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
Target(s): Thyroid hormone receptor(THR)
Signaling pathway(s): Endocrinology/Hormones
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
It is recommended to sonicate at a lower frequency
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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