| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | 2 arylpropionyl CoA epimerase;2 methylacyl CoA racemase;2-methylacyl-CoA racemase;Alpha methylacyl CoA racemase;Alpha methylacyl Coenzyme A racemase;Alpha methylacyl-CoA racemase deficiency, included;Alpha-methylacyl-CoA racemase;Amacr;AMACR deficiency, included;AMACR_HUMAN;CBAS4;Da1-8;Macr1;Methylacyl CoA racemase alpha;RACE;RM |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human AMACR AA range: 300-382 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® AMACR (ABT-AMACR) Mouse Monoclonal Antibody (WM1507) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against AMACR. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | AMACR |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-AMACR |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human AMACR protein. In western blotting of Hela and LnCap cell lysates, the antibody can label a 42 kDa band corresponding to AMACR. |
| Molecular Weight | Calculated: 42 kDa | Observed: 42 kDa |
| UniProt / Swiss-Prot | Q9UHK6 (Human) |
Recommended dilutions: IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human AMACR AA range: 300-382
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
AMACR is an α Formyl COA racemase localized in peroxisomes and mitochondria . It is an enzyme involved in biosynthesis of bile acid and β-oxidation of branched-chain fatty acids. It is expressed in the epithelium and salivary gland of proximal convoluted tubules of pancreas, liver and kidney, and moderately in paraurethral glands. The expression in prostate cancer is higher than that in benign prostate tissue. In the study of prostate cancer, it is often used in combination with PSA, p63, 34 β E12 and other antibodies.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:100-500;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-AMACR.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
