| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | BECN1 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthetic Peptide of Beclin-1 at AA range of 110-190 |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Beclin-1 Mouse Monoclonal Antibody (5C2) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Beclin 1. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence and reacts with Human, Rat, Mouse, Bovine.
Validated Applications
| Target | Beclin 1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5C2 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse, Bovine |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | Beclin-1 protein detects endogenous levels of BECN1 |
| Molecular Weight | Observed: 60 kDa |
| UniProt / Swiss-Prot | Q14457 (Human) | O88597 (Mouse) | Q91XJ1 (Rat) |
Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
Immunogen / Antigen
Synthetic Peptide of Beclin-1 at AA range of 110-190
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse, Bovine. Confirm suitability for untested species before use.
Scientific Background
beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence. Recommended dilutions: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
Confirmed reactivity: Human, Rat, Mouse, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 5C2.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
