| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | b-catenin;Beta catenin;Beta-catenin;Cadherin associated protein;Catenin;cadherin associated protein;, beta 1, 88 kDa;Catenin beta 1;Catenin beta-1;CATNB;CHBCAT;CTNB1_HUMAN;CTNNB;CTNNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Beta-catenin AA range: 700-781 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Beta-catenin (ABT-Catenin) Mouse Monoclonal Antibody (WM1286) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Catenin-β. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Catenin-β |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-Catenin |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human β- Catenin protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody labels β- Cateninn, no reaction with α or γ-catenin. |
| Molecular Weight | Calculated: 84 kDa | Observed: 94 kDa |
| UniProt / Swiss-Prot | P35222 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Beta-catenin AA range: 700-781
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
β- Catenin is a key regulatory protein in Wnt signaling pathway. Under normal conditions, β- Catenin protein is mainly found in the cell membrane of normal cells. It leads to accumulation in the nucleus after mutation. It is mainly used for the diagnosis, invasion and metastasis mechanism of malignant tumors, such as colon cancer, lung cancer, prostate cancer, esophageal cancer, breast cancer and so on.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-Catenin.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
