| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | CAD;CALD 1;CALD1;CALD1_HUMAN;Caldesmon 1;Caldesmon 1 Isoform 1;Caldesmon 1 Isoform 2;Caldesmon 1 Isoform 3;Caldesmon 1 Isoform 4;Caldesmon 1 Isoform 5;Caldesmon;Caldesmon1;CDM;H CAD;HCAD;L CAD;LCAD;MGC21352;NAG22 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Caldesmon pan AA range: 100-200 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Caldesmon (ABT125) Mouse Monoclonal Antibody (WM1295) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Caldesmon. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | Caldesmon |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT125 |
| Isotype | IgG2a, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can recognize human h-caldesmon and l-caldesmon protein. In western blotting , the antibody labels a 93 kDa band. |
| Molecular Weight | Calculated: 93 kDa | Observed: 93 kDa |
| UniProt / Swiss-Prot | Q05682 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Caldesmon pan AA range: 100-200
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Caldesmon is a binding protein of smooth muscle actin and calmodulin. It is a cytoskeleton related protein with the function of regulating smooth muscle contraction. In clinical diagnosis, it is used to label smooth muscle cells and cells with smooth muscle differentiation, identify myofibroblastoma from true leiomyoma, and combine CD10 to identify endometrial stromal sarcoma and uterine smooth muscle tumor.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT125.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
