| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | AHUS 6;AHUS6;BDCA 3;BDCA3;CD 141;CD141;CD141 antigen;Fetomodulin;Thbd;THPH12;THRM;Thrombomodulin;TM;TRBM_HUMAN |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human CD141 AA range: 50-150 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CD141 (ABT145) Mouse Monoclonal Antibody (WM1301) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD141. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | CD141 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT145 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CD141 protein. |
| Molecular Weight | Calculated: 62 kDa | Observed: 100 kDa |
| UniProt / Swiss-Prot | P07204 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human CD141 AA range: 50-150
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
CD141 is a 75 kDa transmembrane glycoprotein expressed in many normal tissues, such as arterial and venous endothelial cells and mesothelial cells. CD141 is not expressed in liver adenocarcinoma. CD141 protein is a sensitive marker of lymphatic endothelial cells and their tumors. It can be used to distinguish lung adenocarcinoma from malignant mesothelioma.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT145.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
