| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | CD 2;CD2;CD2 antigen;p50;, sheep red blood cell receptor;CD2 antigen;CD2 molecule;CD2_HUMAN;Erythrocyte receptor;FLJ46032;LFA-2;LFA-3 receptor;LFA2;LFA3 receptor;Ly-37;Lymphocyte function antigen 2;lymphocyte-function antigen-2;OTTHUMP00000024366;Rosette receptor;Sheep erythrocyte receptor;SRBC;T cell surface antigen CD2;T-cell surface antigen CD2;T-cell surface antigen T11/Leu-5;T-lymphocyte surface CD2 antigen;T11 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human CD2 AA range: 1-100 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CD2 (ABT529) Mouse Monoclonal Antibody (WM1310) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD2. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | CD2 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT529 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CD2 protein. |
| Molecular Weight | Calculated: 39 kDa | Observed: 50 kDa |
| UniProt / Swiss-Prot | P06729 (Human) | P08920 (Mouse) | P08921 (Rat) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human CD2 AA range: 1-100
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
CD2 is a 50-55 kDa transmembrane glycoprotein present on all peripheral T cells, lymphocytes and NK cells. The main function is to regulate activated T cells and mediate thymocyte thymic epithelial adhesion. CD2 expression may be abnormally absent in T-cell lymphoma, which is helpful to distinguish reactive T-cell proliferation. It is mainly used for the diagnosis and differentiation of tumors derived from T cells and NK cells.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT529.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
