| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | C3DR;CD 21;CD21;Complement C3d receptor 2;Complement C3d receptor;Complement component;3d/Epstein Barr virus;receptor 2;Complement receptor type 2;CR;Cr2;CR2_HUMAN;CVID7;EBV receptor;EBV-R;Epstein Barr virus receptor;Epstein-Barr virus receptor;EVBR;SLEB9 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human CD21 AA range: 400-500 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CD21 (ABT-CD21) Mouse Monoclonal Antibody (WM1317) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD21. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | CD21 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-CD21 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CD21 protein. |
| Molecular Weight | Calculated: 113 kDa | Observed: 160 kDa |
| UniProt / Swiss-Prot | P20023 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human CD21 AA range: 400-500
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
CD21, also known as type 2 complement receptor, is an important marker of B lymphocytes and EB virus receptor. It is a member of the complement activation regulator family. CD21 is mainly distributed in mature B cells, dendritic cells in lymphoid follicles and some T cells. It can promote the proliferation of B cells, participate in immune memory and mediate the transformation of EBV into B cells. It is mainly used for the diagnosis of follicular dendritic cell tumor and the study of immune complement activation regulation.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-CD21.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
