| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | BDPLT16;BDPLT2;CD 61;CD61;CD61 antigen;GP3A;GPIIIa;GT;HPA 1;HPA 4;Integrin beta 3;platelet glycoprotein IIIa antigen CD61;Integrin beta chain beta 3;Integrin beta-3;ITB3_HUMAN;ITG B3;ITGB 3;ITGB3;NAIT;platelet fibrinogen receptor;Platelet fibrinogen receptor beta subunit;Platelet fibrinogen receptor, beta subunit;Platelet glycoprotein IIIa;Platelet glycoprotein IIIa precursor;Platelet membrane glycoprotein IIIa;PTP |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human CD61 AA range: 1-100 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CD61 (ABT032) Mouse Monoclonal Antibody (WM1390) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Integrin β3. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | Integrin β3 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT032 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CD61 protein. |
| Molecular Weight | Calculated: 87 kDa | Observed: 70 kDa |
| UniProt / Swiss-Prot | P05106 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human CD61 AA range: 1-100
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
CD61 is also known as integrin β 3, a 105 kDa membrane glycoprotein, is an integrin cell surface protein related to cell adhesion and cell surface mediated signal transduction. It is expressed on platelets, megakaryocytes, osteoclasts and vascular endothelial cells. CD61 and CD41 form platelet glycoprotein IIb / IIIB complex and participate in coagulation and thrombosis. It is mainly used to detect small megakaryocytes in platelet and bone marrow biopsy, and can also be used in the diagnosis of megakaryocytic leukemia.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT032.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
