| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | B lymphocyte-specific MB1 protein;B-cell antigen receptor complex-associated protein alpha chain;CD 79a;CD79a;CD79a antigen;immunoglobulin-associated alpha;CD79A antigen;CD79a molecule, immunoglobulin-associated alpha;CD79A_HUMAN;Ig alpha;Ig-alpha;IGA;IgM-alpha;Immunoglobulin-associated alpha;Ly54;MB-1 membrane glycoprotein;MB1;Membrane-bound immunoglobulin-associated protein;Surface IgM-associated protein |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human CD79a AA range: 100-226 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CD79a (ABT-CD79a) Mouse Monoclonal Antibody (WM1394) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD79A. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Rat.
Validated Applications
| Target | CD79A |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-CD79a |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CD79a protein. |
| Molecular Weight | Calculated: 25 kDa | Observed: 39 kDa |
| UniProt / Swiss-Prot | P11912 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human CD79a AA range: 100-226
Reactivity Notes
Confirmed cross-reactivity: Human, Rat. Confirm suitability for untested species before use.
Scientific Background
CD79a and CD79b form a heterodimer molecular complex. Together with the membrane surface immunoglobulin of B cells, they form the antigen recognition receptor of B cells, participate in the signal transduction of B cell activation, and can be a broad-spectrum marker of B cells. They can be labeled from the former B cells to mature plasma cells. Because the expression of CD79a decreased during terminal differentiation, the staining may be due to the cross reaction of CD79b. It is often used in combination with other antibodies for the diagnosis of B-cell lymphoma.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-CD79a.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
