| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | COX 2;COX-2;COX2;Cyclooxygenase 2;Cyclooxygenase 2b;Cyclooxygenase;Cyclooxygenase-2;Cyclooxygenase2;fj02a10;Glucocorticoid-regulated inflammatory cyclooxygenase;Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase;GRIPGHS;hCox 2;Macrophage activation-associated marker protein P71/73;OTTHUMP00000033524;PES-2;PGG/HS;PGH synthase 2;PGH2_HUMAN;PGHS 2;PGHS-2;PGHS2;PHS 2;PHS II;PHS2;Prostaglandin endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin endoperoxide synthase 2;Prostaglandin G/H synthase 2;Prostaglandin G/H synthase 2 precursor;Prostaglandin G/H synthase and cyclooxygenase;Prostaglandin G/H synthase;Prostaglandin H2 synthase 2;prostaglandin-endoperoxide synthase 2;prostaglandin G/H synthase and cyclooxygenase;Prostaglandin-endoperoxide synthase 2;PTGS2;ptgs2a;TIS10;TIS10 protein;unp1239;wu:fj02a10 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human COX-2 (cyclooxygenase-2) AA range: 500-604 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® COX-2 (ABT-COX2) Mouse Monoclonal Antibody (WM1482) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against COX2. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | COX2 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-COX2 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human COX-2 protein. In western blotting of Hela and A549 cell lysates, the antibody can label a 70 kDa band corresponding to COX-2. |
| Molecular Weight | Calculated: 69 kDa | Observed: 70 kDa |
| UniProt / Swiss-Prot | P35354 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human COX-2 (cyclooxygenase-2) AA range: 500-604
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
COX has two isomeric forms of COX-1 and COX-2. It is a membrane-bound protease involved in the conversion of arachidonic acid to prostaglandins. COX-2 is an inducible enzyme that participates in the expression of cell growth factors, tumor promoting factors and cytokines, and is highly expressed in breast, lung, and colon cancers. It is mainly used in tumor research and is one of the targets of tumor therapy.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-COX2.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
