| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | 47 kDa cytokeRatin;CK-13;CK13;Cytokeratin 13;CytokeRatin-13;K13;K1C13_HUMAN;Ka13;KeRatin 13;KeRatin;keRatin type I cytoskeletal 13;KeRatin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keRatin Ka13;WSN2 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Cytokeratin 13 AA range: 400-458 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Cytokeratin 13 (ABT-CK13) Mouse Monoclonal Antibody (WM1397) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cytokeratin 13. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | Cytokeratin 13 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-CK13 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CK13 protein. In western blotting of A431 cell lysate, the antibody can label a 50 kDa band corresponding to CK13. |
| Molecular Weight | Calculated: 50 kDa | Observed: 50 kDa |
| UniProt / Swiss-Prot | P13646 (Human) | P08730 (Mouse) | Q6IFV4 (Rat) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Cytokeratin 13 AA range: 400-458
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Cytokeratin 13 (CK13) is a 54 kDa protein which belongs to the intermediate filament family. CK13 protein is highly expressed in normal tissues and gradually decreased or disappeared in malignant tissues. Defects in the CK13 gene may lead to white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia. CK13 can be used as an auxiliary indicator in the diagnosis of precancerous lesions.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-CK13.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
