| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | 39.1;CK 17;CK-17;CytokeRatin-17;K17;K1C17_HUMAN;KeRatin 17;keRatin 17 epitope S1;keRatin 17 epitope S2;keRatin 17 epitope S4;KeRatin 17, type I;KeRatin;KeRatin type I cytoskeletal 17;keRatin, type i cytoskeletal 17 [version 1];KeRatin-17;KRT17;PC;PC2;PCHC1;type I cytoskeletal 17 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Cytokeratin 17 AA range: 300-432 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Cytokeratin 17 (ABT-CK17) Mouse Monoclonal Antibody (WM1400) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cytokeratin 17. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Cytokeratin 17 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-CK17 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17. |
| Molecular Weight | Calculated: 48 kDa | Observed: 48 kDa |
| UniProt / Swiss-Prot | Q04695 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Cytokeratin 17 AA range: 300-432
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-CK17.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
