| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | wu:fb34h11;ALXDRD;cb345;etID36982.3;FLJ42474;FLJ45472;GFAP;GFAP_HUMAN;gfapl;Glial fibrillary acidic protein;Intermediate filament protein;wu:fk42c12;xx:af506734;zgc:110485 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human Glial Fibrillary Acidic Protein AA range: 300-432 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Glial Fibrillary Acidic Protein (GFAP) (ABT176) Mouse Monoclonal Antibody (WM1424) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Glial Fibrillary Acidic Protein. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Rat, Monkey, Bovine.
Validated Applications
| Target | Glial Fibrillary Acidic Protein |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT176 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Monkey, Bovine |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human GFAP protein. |
| Molecular Weight | Calculated: 49 kDa | Observed: 50 kDa |
| UniProt / Swiss-Prot | P14136 (Human) | P03995 (Mouse) | P47819 (Rat) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human Glial Fibrillary Acidic Protein AA range: 300-432
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Monkey, Bovine. Confirm suitability for untested species before use.
Scientific Background
GFAP is an intermediate filament protein with a molecular weight of 51 kDa, which participates in the formation of cytoskeleton and maintains its tension strength. GFAP is mainly distributed in astrocytes and ependymal cells of the central nervous system, Schwann cells and satellite cells of intestinal ganglion of the peripheral nervous system, myoepithelial cells and chondroblasts. It is mainly used for the diagnosis and differential diagnosis of astrocytoma, including astrocytoma, astroblastoma, mixed glioma, pleomorphic glioblastoma and non astrocytoma, including a few gliomas, most ependymomas and other central nervous system tumors.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Rat, Monkey, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT176.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
