| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | GSTP1 FAEES3 GST3 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human GST-Pi AA range: 150-210 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® GST-Pi (ABT-GSTP1) Mouse Monoclonal Antibody (WM1497) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against GST-Pi. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | GST-Pi |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-GSTP1 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human GST-Pi protein. In western blotting of Hela cell lysate, the antibody can label a 26 kDa band corresponding to GST-Pi. |
| Molecular Weight | Calculated: 23 kDa | Observed: 26 kDa |
| UniProt / Swiss-Prot | P09211 (Human) | P19157 (Mouse) | P04906 (Rat) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human GST-Pi AA range: 150-210
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
GST -Pi is a major isoenzyme in GST family. It widely exists in the cytoplasm and mitochondria of human organs and has detoxification function. At present, it is considered to be a marker of drug resistance in tumor cells. GST - Pi is highly expressed in a variety of tumors, which is related to tumor treatment drug resistance. The simultaneous detection of GST - Pi with P-gp and TopoII has more clinical significance for judging whether tumor cells produce drug resistance.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-GSTP1.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
