| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ST13;AAG2;FAM10A1;HIP;SNC6;Hsc70-interacting protein;Hip;Aging-associated protein 2;Progesterone receptor-associated p48 protein;Protein FAM10A1;Putative tumor suppressor ST13;Renal carcinoma antigen NY-REN-33;Suppression of tum |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Purified recombinant human Hip protein fragments expressed in E.coli. |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Hip Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Hip. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence and reacts with Human, Bovine, Dog, Pig.
Validated Applications
| Target | Hip |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Bovine, Dog, Pig |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | Hip Monoclonal Antibody detects endogenous levels of Hip protein. |
| Molecular Weight | Calculated: 41 kDa |
| UniProt / Swiss-Prot | P50502 (Human) | Q99L47 (Mouse) |
Recommended dilutions: WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.
Immunogen / Antigen
Purified recombinant human Hip protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Bovine, Dog, Pig. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence. Recommended dilutions: WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.
Confirmed reactivity: Human, Bovine, Dog, Pig. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
