| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Interferon regulatory factor 4;IRF 4;IRF-4;Irf4;IRF4_HUMAN;LSIRF;Lymphocyte specific interferon regulatory factor;Lymphocyte specific IRF;Lymphocyte-specific interferon regulatory factor;Multiple myeloma oncogene 1;MUM 1;MUM1;NF EM5;NF-EM5;NFEM5;PU.1 interaction partner;Sfpi1/PU.1 interaction partner;Transcriptional activator PIP |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human MUM1 AA range: 350-451 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® IRF-4/MUM1 (ABT080) Mouse Monoclonal Antibody (WM1432) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against MUM1. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | MUM1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT080 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human MUM1 protein. |
| Molecular Weight | Calculated: 52 kDa | Observed: 52 kDa |
| UniProt / Swiss-Prot | Q15306 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human MUM1 AA range: 350-451
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT080.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
