| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | AIS;Amplified in squamous cell carcinoma;B;p51A;B;p51B;Chronic ulceRative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;KeRatinocyte transcription factor;KeRatinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63_HUMAN;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human p63 AA range: 600-680 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® p63 (ABT-P63) Mouse Monoclonal Antibody (WM1442) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against p40/p63. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | p40/p63 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-P63 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | The antibody can specifically recognize human p63 protein, including ΔNp63 and TAp63. In western blotting of A431, Hela cell lysates, the antibody can label a 77 kDa band corresponding to p63, while there is no band detected in p63 knock out Hela cell lysate. |
| Molecular Weight | Calculated: 77 kDa | Observed: 77 kDa |
| UniProt / Swiss-Prot | Q9H3D4 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Immunogen / Antigen
Synthesized peptide derived from human p63 AA range: 600-680
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
P63 is a nuclear protein transcription factor located on chromosome 3q27-29. It is a member of p53 gene family and plays an important role in the growth and development of a variety of epithelial organs. P63 was localized in the basal cells of squamous epithelium and urethral epithelium, myoepithelial cells of breast, sweat gland and salivary gland, basal cells of prostate and basal cells of skin squamous epithelium. P63 is a marker of basal cell carcinoma, squamous cell carcinoma and urinary tract transitional cell carcinoma. It can be used in the study of primary skin tumors, metastatic adenocarcinoma, benign and malignant breast lesions and prostate cancer.
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-P63.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
