Vistusertib

SKU:BHB20410261
Overview
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Vistusertib (CAS 1009298-59-2) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 1009298-59-2
Molecular Weight 462.54 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T1961-1MG 1 mg
T1961-5MG 5 mg
T1961-1MLX10MM 1 mL x 10 mM (in DMSO)
T1961-10MG 10 mg
T1961-25MG 25 mg
T1961-50MG 50 mg
T1961-100MG 100 mg
T1961-200MG 200 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T1961
Activity
  • Kinase Inhibitor
Alternative Names AZD2014
Cas No. 1009298-59-2
Molecular Weight 462.54
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Autophagy///Apoptosis///PI3K/Akt/mTOR signaling///Cytoskeletal Signaling///MAPK
SMILES C(CH)1N(C=2C3=C(N=C(N2)N4(CH)(C)COCC4)N=C(C=C3)C5=CC(C(NC)=O)=CC=C5)CCOC1
Target PI3K///Apoptosis///Autophagy///mTOR///S6 Kinase///Akt

Compound Overview

Vistusertib (CAS 1009298-59-2) is a research-grade small molecule supplied by TargetMol.

Alternative names: AZD2014

Physical Properties

CAS Number 1009298-59-2
Molecular Formula C25H30N6O3
Molecular Weight 462.54 g/mol
SMILES C(CH)1N(C=2C3=C(N=C(N2)N4(CH)(C)COCC4)N=C(C=C3)C5=CC(C(NC)=O)=CC=C5)CC…
Form Solid
Shipping Room Temperature (RT)

Biological Activity

Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.

Target(s): PI3K, Apoptosis, Autophagy, mTOR, S6 Kinase, Akt

Signaling pathway(s): Autophagy, Apoptosis, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, MAPK

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

I need a total of 500 mg of the product for animal experiments, but it won't be used up all at once. How should I dissolve it?

Determining the amount based on solution clarity.1. If the prepared solution is clear, it can be prepared in a larger amount for one-time use and stored at 4°C. It is recommended to prepare the solution once a week, as prolonged storage may lead to loss of efficacy. 2. If the prepared solution is a suspension, it is recommended to prepare and use immediately each time.

What should I do if the product colors are different after multiple purchases?

Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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