| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
WRR139 (CAS 2138924-36-2) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2138924-36-2 |
|---|---|
| Molecular Formula | C25H32N2O4S |
| Molecular Weight | 456.60 g/mol |
| SMILES | (CH)(CCC1=CC=CC=C1)(NC(C=CS(=O)(=O)C2=CC=C(C)C=C2)=O)C(NCCC(C)C)=O |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
WRR139, a peptide vinyl sulfone, plays a role in disease processes including inflammation and cancer, and acts as an inhibitor of cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1. Moreover, WRR139 amplifies the cytotoxic effects of Carfilzomib on cancer cells (1).
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Insoluble impurities, which do not affect the product activity, are recommended to filter out or remove. We will investigate to confirm whether the impurity was introduced during packaging or if it is inherent to the product itself.
For normal mice, the concentration of DMSO should be kept below 10%. For nude mice, transgenic mice, or mice with weak tolerance, the concentration of DMSO should be kept below 2%. For inhibitors being used for the first time, it is recommended to perform a solvent-negative control experiment to confirm that the solvent has no nonspecific effects on the animals.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
