| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
zapnometinib (CAS 303175-44-2) is a research-grade small molecule supplied by TargetMol.
Alternative names: 2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid
Physical Properties
| CAS Number | 303175-44-2 |
|---|---|
| Molecular Formula | C13H7ClF2INO2 |
| Molecular Weight | 409.55 g/mol |
| SMILES | N(C1=C(C(O)=O)C=CC(F)=C1F)C2=C(Cl)C=C(I)C=C2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Zapnometinib (ATR-002) is a MEK inhibitor.
Target(s): Antibacterial, Influenza Virus, MEK
Signaling pathway(s): MAPK, Microbiology/Virology
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
It is not recommended to store DMSO stock solutions at room temperature. Once the stock solution is prepared, aliquot into single-use volumes and store at −20 °C (or −80 °C for sensitive compounds). Room-temperature storage accelerates chemical degradation and moisture uptake. When ready to use, thaw an aliquot at room temperature, use immediately, and avoid repeated freeze-thaw cycles.
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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