| Field | Specification |
|---|---|
| Alternative names | ZM-306416 |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C16H13ClFN3O2 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble in DMSO (3 mg/ml) or ethanol (1 mg/ml) |
| SMILES | |
| InChIKey | |
| Form | Off-white solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
ZM 306416 is a potent and selective inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases, particularly Flk-1 (KDR) and Flt. In neuroscience, ZM 306416 is used to explore the role of VEGF signaling in neurovascular function, blood-brain barrier integrity, and neuroinflammation. Its ability to modulate angiogenic pathways makes it a useful tool in studying neurovascular contributions to neurodegenerative diseases such as Alzheimer’s and multiple sclerosis.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
ZM 306416 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-487)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. Kawai, T., et al. (2006) Neurosci. 141(3): 1209–1216.
