Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters

Other formats: Detergent micelle · VLP

Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer

908 products

Product	Product Type	Application	Price	Status	ACTION
New Human PROKR1-Strep full length protein-synthetic nanodisc Target: PROKR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human PTGER4-Strep full length protein-synthetic nanodisc Target: PTGER4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human SLC1A5-Strep full length protein-synthetic nanodisc Target: SLC1A5	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human SLC2A12-Strep full length protein-synthetic nanodisc Target: SLC2A12	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human P2RX7-Strep full length protein-synthetic nanodisc Target: P2RX7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human SLC2A4-Strep full length protein-synthetic nanodisc Target: SLC2A4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human PROM1-Strep full length protein-synthetic nanodisc Target: PROM1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human PVRIG-Strep full length protein-synthetic nanodisc Target: PVRIG	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human SLC25A4-Strep full length protein-synthetic nanodisc Target: SLC25A4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human SCN5A full length protein-synthetic nanodisc Target: SCN5A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SLC34A2 full length protein-synthetic nanodisc Target: SLC34A2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human QRFPR full length protein-synthetic nanodisc Target: QRFPR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SCAP full length protein-synthetic nanodisc Target: SCAP	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SCN2A full length protein-synthetic nanodisc Target: SCN2A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PTPRZ1 full length protein-synthetic nanodisc Target: PTPRZ1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PLA2R1 full length protein-synthetic nanodisc Target: PLA2R1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PROKR1 full length protein-synthetic nanodisc Target: PROKR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PTGDR2 full length protein-synthetic nanodisc Target: PTGDR2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SCARB1 full length protein-synthetic nanodisc Target: SCARB1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PTGER4 full length protein-synthetic nanodisc Target: PTGER4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PTGER2 full length protein-synthetic nanodisc Target: PTGER2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SLC2A12 full length protein-synthetic nanodisc Target: SLC2A12	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SLC1A5 full length protein-synthetic nanodisc Target: SLC1A5	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SLC2A4 full length protein-synthetic nanodisc Target: SLC2A4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PROM1 full length protein-synthetic nanodisc Target: PROM1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human P2RX7 full length protein-synthetic nanodisc Target: P2RX7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human PVRIG full length protein-synthetic nanodisc Target: PVRIG	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human SLC25A4 full length protein-synthetic nanodisc Target: SLC25A4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human NMDE4-Strep full length protein-synthetic nanodisc Target: NMDE4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMDE2-Strep full length protein-synthetic nanodisc Target: NMDE2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMDZ1-Strep full length protein-synthetic nanodisc Target: NMDZ1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMD3A-Strep full length protein-synthetic nanodisc Target: NMD3A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMD3B-Strep full length protein-synthetic nanodisc Target: NMD3B	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMDE3-Strep full length protein-synthetic nanodisc Target: NMDE3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NMDE1-Strep full length protein-synthetic nanodisc Target: NMDE1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human NUDT9-Strep full length protein-synthetic nanodisc Target: NUDT9	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

Consideration	Nanodisc	Detergent micelle	VLP
Lipid environment	Native lipid bilayer disc	Detergent shell (lipids removed)	Native membrane on a capsid
Native function preserved	High	Variable — often reduced for GPCRs	High (keeps oligomeric state)
Best structural method	Single-particle cryo-EM	X-ray crystallography / LCP	Not for high-resolution structure
Display / valency	Monomeric, defined stoichiometry	Monomeric	Multivalent — many copies per particle
Typical particle	~9–13 nm disc	Protein–detergent micelle	~100 nm engineered capsid
Best for	Function + cryo-EM, SPR / BLI binding	Broad selection, high-res X-ray, cost	Immunization, antibody discovery, vaccines
Watch-outs	Disc size caps very large complexes	May alter GPCR conformation / stability	Less suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).