Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters
Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer
908 products
Image ProductProduct Type ApplicationPrice Status ACTION
Negative control-synthetic nanodisc – Figure 1 of 1
New
Recombinant Protein Functional Assay (In Vitro) ELISA
From $630.00
Regular price From $630.00
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: AQP5
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Other Protein Functional Assay (In Vitro) ELISA
From $1,820.00
Regular price From $1,820.00
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: CCR8
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Chemokine Functional Assay (In Vitro) ELISA
From $1,078.00
Regular price From $1,078.00
Made to Order
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: lspA
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Enzyme & Protease Functional Assay (In Vitro) ELISA
From $1,820.00
Regular price From $1,820.00
Made to Order
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: lgt
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Enzyme & Protease Functional Assay (In Vitro) ELISA
From $1,820.00
Regular price From $1,820.00
Made to Order
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: ADTRP
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Other Protein Functional Assay (In Vitro) ELISA
From $1,820.00
Regular price From $1,820.00
Made to Order
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: aqpZ
Proteins & Peptides, Recombinant Proteins, Transmembrane Proteins, CF Transmembrane Proteins, Other Protein Functional Assay (In Vitro) ELISA
From $1,820.00
Regular price From $1,820.00
Made to Order
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: agrC
Proteins & Peptides, Recombinant Proteins, Viral & Microbial Antigen Enzyme Activity
From $1,620.00
Regular price From $1,620.00
Human TRPV3-Strep full length protein-synthetic nanodisc
New
Target: TRPV3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM8-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: TRPM8
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPV2-Strep full length protein-synthetic nanodisc
New
Target: TRPV2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPV5-Strep full length protein-synthetic nanodisc
New
Target: TRPV5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC1-Strep full length protein-synthetic nanodisc
New
Target: TRPC1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM3-Strep full length protein-synthetic nanodisc
New
Target: TRPM3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM6-Strep full length protein-synthetic nanodisc
New
Target: TRPM6
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM7-Strep full length protein-synthetic nanodisc
New
Target: TRPM7
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM2-Strep full length protein-synthetic nanodisc
New
Target: TRPM2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM1-Strep full length protein-synthetic nanodisc
New
Target: TRPM1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM5-Strep full length protein-synthetic nanodisc
New
Target: TRPM5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPV4-Strep full length protein-synthetic nanodisc
New
Target: TRPV4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC4-Strep full length protein-synthetic nanodisc
New
Target: TRPC4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human ZACN-Strep full length protein-synthetic nanodisc
New
Target: ZACN
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC7-Strep full length protein-synthetic nanodisc
New
Target: TRPC7
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPM4-Strep full length protein-synthetic nanodisc
New
Target: TRPM4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC3-Strep full length protein-synthetic nanodisc
New
Target: TRPC3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC6-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: TRPC6
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TRPC5-Strep full length protein-synthetic nanodisc
New
Target: TRPC5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TM40-Strep full length protein-synthetic nanodisc
New
Target: TM40
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TTYH1-Strep full length protein-synthetic nanodisc
New
Target: TTYH1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human TOM40-Strep full length protein-synthetic nanodisc
New
Target: TOM40
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VIPR1-Strep full length protein-synthetic nanodisc
New
Target: VIPR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VDAC3-Strep full length protein-synthetic nanodisc
New
Target: VDAC3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VN1R1-Strep full length protein-synthetic nanodisc
New
Target: VN1R1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VDAC2-Strep full length protein-synthetic nanodisc
New
Target: VDAC2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VDAC1-Strep full length protein-synthetic nanodisc
New
Target: VDAC1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human VIPR2-Strep full length protein-synthetic nanodisc
New
Target: VIPR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

ConsiderationNanodiscDetergent micelleVLP
Lipid environmentNative lipid bilayer discDetergent shell (lipids removed)Native membrane on a capsid
Native function preservedHighVariable — often reduced for GPCRsHigh (keeps oligomeric state)
Best structural methodSingle-particle cryo-EMX-ray crystallography / LCPNot for high-resolution structure
Display / valencyMonomeric, defined stoichiometryMonomericMultivalent — many copies per particle
Typical particle~9–13 nm discProtein–detergent micelle~100 nm engineered capsid
Best forFunction + cryo-EM, SPR / BLI bindingBroad selection, high-res X-ray, costImmunization, antibody discovery, vaccines
Watch-outsDisc size caps very large complexesMay alter GPCR conformation / stabilityLess suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).

Recommended nanodisc products

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