Sensitive and accurate. Use as little as 60 uL samples. Linear detection range in 96-well plate: 5 to 1000 uM sialic acid for colorimetric assays and 0.5 to 100 uM for fluorimetric assays.
Intended Use
OD549nm,or FL555/585nm
Detection Principle
OD, FL: 5, 0.5 uM
Sample Type
Serum
Shelf Life
24 months
Specifity
For quantitative determination of free and total sialic acid (NANA) and evaluation of drug effects on sialic acid.
Reference
Esievo, K. A. N. et al (2021). Elevated serum sialic acids, a potent biomarker of alloxan-induced type 1 diabetes in dogs by ethanolic extract of Anogeissus leiocarpus. Journal of Diabetes & Metabolic Disorders, 1-8. Assay: sialic acid in dog serum.
Azeez, R. A (2018). The Related Changes Between Diabetic Positive Family History Children'S And Salivary Sialic Acid, Flow rate, Age, Gender In Iraqi Primary School. International Journal of Design and Nature 8(2):245-250. Assay: Sialic Acid in human saliva.
Taib, I.S. et al.(2015) "Palm oil tocotrienol-rich fraction attenuates testicular toxicity induced by fenitrothion via an oxidative stress mechanism." Toxicology Research 4.1: 132-142. Assay: Sialic Acid in rat tissue.
Taib, IS et al (2015). Palm oil tocotrienol-rich fraction attenuates testicular toxicity induced by fenitrothion via an oxidative stress mechanism. Toxicology Research 4.1: 132-142. Assay: SialicAcid in rat tissue.
Gantner, M et all (2014). Partial synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification. Journal of Lipid Research. 55, 2692-2704. Assay: Sialic Acid in bovine brain gangliosides.
Pawluczyk, Izabella ZA, et al (2014). "Sialic acid attenuates puromycin aminonucleoside-induced desialylation and oxidative stress in human podocytes." Experimental cell research 320.2: 258-268. Assay: Sialic Acid in podocytes.
Chrostek, L et al (2013). Sialic acid levels reflects the disturbances of glycosylation and acute-phase reaction in rheumatic diseases. Rheumatology International. 34(3): 393-399. Assay: Sialic Acid in human serum.
Carvalho FA, et al (2011). Variations on fibrinogen-erythrocyte interactions during cell aging. PLoS One. 6(3):e18167. Assay: Sialic Acid in human blood.
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