| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A portin of amino acids 604-748 from the human protein was used as the immunogen for the Alpha-2-M antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
Alpha-2-M Antibody / Alpha-2-Macroglobulin / A2M is an antibody targeting Alpha-2-M. Host: Mouse. Monoclonal. Clone: A2M/3622. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: Alpha-2-M.
- Immunogen: A portin of amino acids 604-748 from the human protein was used as the immunogen for the Alpha-2-M antibody..
- Species reactivity: Human.
- Localization: Secreted in plasma.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
A2-Macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
