| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Aromatase;1.14.14.14;CYPXIX;Cytochrome P-450AROM;Cytochrome P450 19A1;Estrogen synthase;CYP19A1;ARO1, CYAR, CYP19; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Immunogen | A synthesized peptide derived from human Aromatase |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Storage | |
| Target | |
| UniProt # |
Overview
This product is an anti-CYP19A1 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone AABB-3; isotype Rabbit IgG; reactivity: Human,Rat. Reported application contexts include WB, IP (as provided in the source record). Boster Bio Anti-Aromatase CYP19A1 Rabbit Monoclonal Antibody catalog # M00071. Tested in WB, IP applications. This antibody reacts with Human, Rat.
Key elements and design rationale
- Target: CYP19A1 (Aromatase).
- Antibody format: Monoclonal; clone AABB-3; isotype Rabbit IgG.
- Host: Rabbit.
- Species reactivity: Human,Rat (confirm in your model system with appropriate controls).
This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.
Biological background
CYP19A1 (protein: P2X purinoceptor 1) is a commonly studied target in molecular and cellular biology. Functional context (as provided): Catalyzes the formation of aromatic C18 estrogens from C19 androgens. Reported cellular localization context: Membrane; Peripheral membrane protein. Tissue expression notes (as provided): Brain, placenta and gonads. .
Research relevance and current trends
- Research context keywords from the source record include: Cancer,Cardiovascular,Cytochromes,Drug Metabolism,Growth Factors/Hormones,Lipases,Lipid and Lipoprotein Metabolism,Lipid Metabolism,Lipids/Lipoproteins,Metabolic Signaling Pathways,Metabolism,Mitochondrial Metabolism,Pathways and Processes,Signal Transduction.
- Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
- Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.
Common research applications
- Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
- Immunoprecipitation (IP): enrich target complexes for downstream immunoblot or interaction analyses.
Workflow ideas (metafield): Validate CYP19A1 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect CYP19A1 expression by Western blot in cell or tissue lysates, Enrich CYP19A1 by immunoprecipitation from lysates for downstream analysis
Notes for experimental interpretation
- Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
- Apparent molecular weight may vary by sample type and processing (observed MW: 50 kDa; calculated MW: 58 kDa).
- Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.
Additional product details (from the source record)
- Molecular weight (observed): 50 kDa
- Cellular localization (provided): Membrane; Peripheral membrane protein.
- Tissue details (provided): Brain, placenta and gonads. .
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
