| Field | Specification |
|---|---|
| Target | |
| Alternative names | Calponin-2;Calponin H2, smooth muscle;Neutral calponin;Cnn2; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Turkey gizzard calponin |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone CP-93 is a mouse monoclonal antibody that recognizes calponin-2 (gene Cnn2) in chicken, human and turkey samples and is validated for Western blot, IHC and ICC/IF.
Calponin-2 (CNN2) is a calponin family member expressed in smooth muscle and many non-muscle cells. It binds actin and tropomyosin and regulates actin cytoskeleton dynamics, influencing cell motility and adhesion, so it is studied in cell migration, macrophage function and tissue remodeling.
| Target | Calponin-2 (gene Cnn2; UniProt Q08093, mouse) |
|---|---|
| Clone | CP-93 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Chicken, Human, Turkey |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | Not specified by the supplier |
|---|---|
| Immunohistochemistry | Not specified by the supplier |
| Immunocytochemistry / Immunofluorescence | Not specified by the supplier |
Immunogen
Turkey gizzard calponin.
Reactivity Notes
The supplier lists reactivity with chicken, human and turkey. Tissue expression noted by UniProt (mouse): Smooth muscle, and tissues containing significant amounts of smooth muscle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Fan Pei et al. (2016) Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells. Scientific Reports. 10.1038/srep30230
Zhang Chen et al. (2019) MiR-449a-5p mediates mitochondrial dysfunction and phenotypic transition by targeting Myc in pulmonary arterial smooth muscle cells. Journal of Molecular Medicine-Jmm. 10.1007/s00109-019-01751-7
Yiyuan Duan et al. (2016) Overexpression of soluble ADAM33 promotes a hypercontractile phenotype of the airway smooth muscle cell in rat. Experimental Cell Research. 10.1016/j.yexcr.2016.10.004
Yuan-yuan Qu et al. (2016) Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension. PLoS One. 10.1371/journal.pone.0157456
Peng Xue et al. (2014) Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries. Molecular and Cellular Biochemistry. 10.1007/s11010-014-2145-9
