| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cathepsin D;3.4.23.5;Cathepsin D 12 kDa light chain;Cathepsin D 9 kDa light chain;Cathepsin D 34 kDa heavy chain;Cathepsin D 30 kDa heavy chain;Ctsd; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Human liver cathepsin D. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone CTD-19 is a mouse monoclonal antibody that recognizes cathepsin D (gene Ctsd) in human samples and is validated for Western blot and IHC.
Cathepsin D (CTSD) is a lysosomal aspartic protease that carries out bulk breakdown of proteins in acidic compartments. It also participates in processing of proteins such as amyloid precursor protein. CTSD is studied in lysosomal function, neurodegeneration and breast cancer, where its secretion has been widely investigated.
| Target | Cathepsin D (gene Ctsd; UniProt P24268, rat) |
|---|---|
| Clone | CTD-19 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG2a |
| Reactivity | Human |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 1–2 µg/mL (Human) |
|---|---|
| Western blot | 0.5–1 µg/mL (Human) |
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Human liver cathepsin D.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes cathepsin D as secreted and also located in the lysosome and melanosome.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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