| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cathepsin L1;3.4.22.15;Cathepsin L;Cyclic protein 2;CP-2;Major excreted protein;MEP;Procathepsin L;Cathepsin L1 heavy chain;Cathepsin L1 light chain;Ctsl;Ctsl1; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Procathepsin L isolated from the human lung cancer cell line EPLC 32M1. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 33/2 is a mouse monoclonal antibody that recognizes procathepsin L (gene Ctsl) in human, mouse and rat samples and is validated for Western blot and IHC.
Cathepsin L (CTSL) is a lysosomal cysteine protease that drives general protein turnover. It also has specialized roles: processing antigens and the invariant chain for MHC class II presentation in the thymus, generating neuropeptides from their precursors, and degrading elastin and other matrix components. Cathepsin L also helps some viruses enter cells, so it is studied broadly.
| Target | Procathepsin L (gene Ctsl; UniProt P07154, rat) |
|---|---|
| Clone | 33/2 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human, Mouse, Rat |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| Immunohistochemistry | Not specified by the supplier |
Immunogen
Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes procathepsin L as secreted and also located in the lysosome and apical cell membrane. Tissue expression noted by UniProt (rat): Both mature cathepsin L1 and procathepsin L are found in the upper epidermis.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
