| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | C-C motif chemokine 19;Beta-chemokine exodus-3;CK beta-11;Epstein-Barr virus-induced molecule 1 ligand chemokine;EBI1 ligand chemokine;ELC;Macrophage inflammatory protein 3 beta;MIP-3-beta;Small-inducible cytokine A19;CCL19;ELC, MIP3B, SCYA19; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human CCL19 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody is an antibody targeting CCL19. Common applications include WB. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: AHD-3; isotype: Rabbit IgG; reactivity: Human; observed MW: 92 kDa; calculated MW: 10993 MW.
Boster Bio Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody catalog # M01605. Tested in WB application. This antibody reacts with Human.
Key elements and design rationale
- Target: CCL19 — C-C motif chemokine 19
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: AHD-3; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 92 kDa; Calculated: 10993 MW
Biological background
Protein function (datasheet): May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. .
Cellular localization (datasheet): Secreted.
Tissue details (datasheet): Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Research relevance and current trends
- Commonly studied in contexts related to Chemokines,G Protein Signaling,Immunology,Innate Immunity,Macrophage/Inflammation,Signal Transduction,Signaling Pathway.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
