| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Cyclin-A2;Cyclin-A;Ccna2;Ccna, Cyca; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | Recombinant bovine cyclin A. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1) is an antibody targeting CCNA2. Common applications include WB, ICC. Key specifications include host: Mouse; clonality: Monoclonal; clone: Clone: CY-A1; isotype: Mouse IgG2a; reactivity: Bovine,Human,Mouse; observed MW: 55 kDa; calculated MW: 47269 MW.
Boster Bio Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1) catalog # MA1032. Tested in ICC, WB applications. This antibody reacts with Bovine, Human, Mouse.
Key elements and design rationale
- Target: CCNA2 — Cyclin-A2
- Antibody format: Host: Mouse; Clonality: Monoclonal; Clone: Clone: CY-A1; Isotype: Mouse IgG2a
- Species reactivity: Bovine,Human,Mouse
- Molecular weight guidance: Observed: 55 kDa; Calculated: 47269 MW
Specificity note: No cross reactivity with other proteins.
Biological background
Protein function (datasheet): Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. .
Scientific background (datasheet): The mammalian A-type cyclin family consists of 2 members, cyclin A1 (CCNA1) and cyclin A2 (CCNA2). Human cyclin A gene is assigned to 4q26-q27. Cyclin A protein is synthesized and localized into the nucleus at the onset of S phase in nontransformed mammalian fibroblasts.
Cellular localization (datasheet): Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER. .
Tissue details (datasheet): Ubiquitous. In the testis, expressed in germ cells and in the ovary, in both germline and somatic cells.
Sequence similarities (datasheet): Belongs to the cyclin family. Cyclin AB subfamily.
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Cardiovascular,Cell Biology,Cell Cycle,Epigenetics and Nuclear Signaling,Lipids/Lipoproteins.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunofluorescence / ICC: Visualize subcellular localization and co-localization patterns; consider fixation/permeabilization compatibility and controls.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Cross-reactivity (datasheet): No cross-reactivity with other proteins
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
