| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | DNA damage-binding protein 1; DDB p127 subunit; DNA damage-binding protein a; DDBa; Damage-specific DNA-binding protein 1; HBV X-associated protein 1; XAP-1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; XPE-binding factor; XPE-BF; Xeroderma pigmentosum group E-complementing protein; XPCe; DDB1; XAP1 |
| Clonality | |
| Form | Liquid |
| Host | |
| Immunogen | E. coli - derived recombinant human DDB1 (Gly393-Gln708). |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Overview
Anti-DDB1 Polyclonal Antibody targets DDB1 (Damage-specific DNA-binding protein 1). Frequently used across ELISA, IHC, WB workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Infectious Disease research.
Also known as: Damage-specific DNA-binding protein 1, Xeroderma pigmentosum group E-complementing protein, UV-damaged DNA-binding protein 1, DNA damage-binding protein 1, DNA damage-binding protein a, UV-damaged DNA-binding factor, HBV X-associated protein 1, XPE-binding factor, DDB p127 subunit, UV-DDB 1.
Target biology
DDB1 (Damage-specific DNA-binding protein 1) encodes a DNA-binding transcriptional regulator that influences gene-expression programs. Transcription factors often show context-dependent expression and nuclear localization. Common alternative names and symbols used in the literature include: Xeroderma pigmentosum group E-complementing protein, UV-damaged DNA-binding protein 1, DNA damage-binding protein 1, DNA damage-binding protein a, UV-damaged DNA-binding factor, HBV X-associated protein 1, XPE-binding factor, DDB p127 subunit, UV-DDB 1, XPE-BF. Based on the annotated name/class, the target is most often associated with nucleus localization, though this can vary by model system.
How this antibody helps
As a polyclonal reagent, this antibody can provide strong sensitivity through recognition of multiple epitopes on the target. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Antigen / immunogen context
E. coli - derived recombinant human DDB1 (Gly393-Gln708).
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
- For Western blotting, use fresh protease (and phosphatase, if relevant) inhibitors and confirm the primary band at the expected molecular weight; additional bands may reflect isoforms or processing.
- For IHC, optimize fixation and antigen retrieval (buffer/pH/heat) and include an isotype/secondary-only control to assess background.
- For ELISA, optimize capture/detection pairing and run a standard curve in matrix-matched diluent when possible.
Additional notes
For research use only
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
