| Field | Specification |
|---|---|
| Target | |
| Alternative names | Mucin-1;MUC-1;Breast carcinoma-associated antigen DF3;Cancer antigen 15-3;CA 15-3;Carcinoma-associated mucin;Episialin;H23AG;Krebs von den Lungen-6;KL-6;PEMT;Peanut-reactive urinary mucin;PUM;Polymorphic epithelial mucin;PEM;Tumor-associated epithelial membrane antigen;EMA;Tumor-associated mucin;CD227;Mucin-1 subunit alpha;MUC1-NT;MUC1-alpha;Mucin-1 subunit beta;MUC1-beta;MUC1-CT;MUC1;PUM; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Human milk fat globule membranes. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone GP1.4 is a mouse monoclonal antibody that recognizes mucin-1 (gene MUC1) in human samples and is validated for IHC.
Mucin-1 (MUC1) is a heavily glycosylated transmembrane mucin on the apical surface of most epithelia, forming part of the protective barrier. Its cytoplasmic tail engages signaling pathways including ERK, SRC and NF-κB and can influence p53-regulated transcription. MUC1 is often overexpressed and aberrantly glycosylated in carcinomas, so it is widely studied in cancer biology.
| Target | Mucin-1 (gene MUC1; UniProt P15941, human) |
|---|---|
| Clone | GP1.4 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 2–4 µg/mL (Human) |
|---|---|
| IHC (frozen sections) | 2–4 µg/mL (Human) |
Immunogen
Human milk fat globule membranes.
Reactivity Notes
The supplier lists reactivity with human. UniProt places mucin-1 in the apical cell membrane. Tissue expression noted by UniProt (human): Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Yaoling Liu et al. (2016) Globose, cystic olfactory ensheathing cell tumor: A case report and literature review. Oncology Letters. 10.3892/ol.2016.5131
