| Field | Specification |
|---|---|
| Target | |
| Alternative names | Ferritin heavy chain;Ferritin H subunit;1.16.3.1;Cell proliferation-inducing gene 15 protein;Ferritin heavy chain, N-terminally processed;FTH1;FTH, FTHL6;OK/SW-cl.84, PIG15; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Ferritin Heavy Chain |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 17F96 is a rabbit monoclonal antibody that recognizes ferritin heavy chain (gene FTH1) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 21.2 kDa, and the supplier reports an observed band at about 21 kDa.
Ferritin heavy chain (FTH1) is one of the two subunits of ferritin, the cell's main iron-storage protein. The heavy chain carries the ferroxidase activity that oxidizes Fe2+ to Fe3+ for safe storage inside the ferritin shell. Ferritin can be turned over by NCOA4-mediated ferritinophagy to release iron, so FTH1 is studied in iron homeostasis, oxidative stress and ferroptosis.
| Target | Ferritin heavy chain (gene FTH1; UniProt P02794, human) |
|---|---|
| Clone | 17F96 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 21.2 kDa |
| Observed MW | 21 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human ferritin Heavy Chain.
Reactivity Notes
The supplier lists reactivity with human. UniProt places ferritin heavy chain in the cytoplasm, lysosome and cytoplasmic vesicle. Tissue expression noted by UniProt (human): Expressed in the liver.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Junting Xiao et al. (2021) Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy. Food and Chemical Toxicology. 10.1016/j.fct.2021.112114
