Anti-Ferritin Heavy Chain Rabbit Monoclonal Antibody

Overview

This product is an anti-FTH1 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone 17F96; isotype IgG; reactivity: Human. Reported application contexts include WB, IHC (as provided in the source record). Boster Bio Anti-Ferritin Heavy Chain Rabbit Monoclonal Antibody catalog # M02401-2. Tested in WB, IHC applications. This antibody reacts with Human.

Key elements and design rationale

• Target: FTH1 (Ferritin heavy chain).
• Antibody format: Monoclonal; clone 17F96; isotype IgG.
• Host: Rabbit.
• Species reactivity: Human (confirm in your model system with appropriate controls).

This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.

Biological background

FTH1 (protein: Lysosome-associated membrane glycoprotein 2 (Lamp2)) is a commonly studied target in molecular and cellular biology. Functional context (as provided): Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). . Reported cellular localization context: Nucleus . Tissue expression notes (as provided): Expressed in the liver. .

Research relevance and current trends

• Research context keywords from the source record include: Alzheimer's Disease,Cancer,Cardiovascular,Cofactors, Vitamins/Minerals,Metabolism,Neurodegenerative Disease,Neurology Process,Neuroscience,Pathways and Processes,Serum Proteins,Signal Transduction,Vitamins/Minerals.
• Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
• Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.

Common research applications

• Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
• Immunohistochemistry (IHC): evaluate spatial distribution of target-positive staining in tissue architecture.

Workflow ideas (metafield): Validate FTH1 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect FTH1 expression by Western blot in cell or tissue lysates, Detect FTH1 in FFPE tissue sections by immunohistochemistry

Notes for experimental interpretation

• Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
• Apparent molecular weight may vary by sample type and processing (observed MW: 69 kDa; calculated MW: 21226 MW).
• Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.

Additional product details (from the source record)

• Molecular weight (observed): 69 kDa
• Cellular localization (provided): Nucleus .
• Tissue details (provided): Expressed in the liver. .

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.