| Field | Specification |
|---|---|
| Target | |
| Alternative names | Glucagon;Glicentin;Glicentin-related polypeptide;GRPP;Oxyntomodulin;OXM;OXY;Glucagon;Glucagon-like peptide 1;GLP-1;Glucagon-like peptide 1 (7-37);GLP-1 (7-37);Glucagon-like peptide 1 (7-36);GLP-1 (7-36);Glucagon-like peptide 2;GLP-2;Gcg; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Polymerized porcine glucagon. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone K79bB10 is a mouse monoclonal antibody that recognizes pro-glucagon (gene Gcg) in human, mouse, rabbit and rat samples and is validated for IHC and ICC/IF.
Proglucagon (GCG) is processed into several hormones depending on the tissue. In pancreatic α cells it yields glucagon, which raises blood glucose by stimulating hepatic glucose output, and in intestinal L cells it yields GLP-1 and GLP-2, which boost insulin secretion and support gut growth. GCG products are central to studies of glucose homeostasis, diabetes and obesity.
| Target | Pro-glucagon (gene Gcg; UniProt P06883, rat) |
|---|---|
| Clone | K79bB10 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human, Mouse, Rabbit, Rat |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 1–2 µg/mL (Human, Mouse, Rat, Rabbit) |
|---|---|
| Immunocytochemistry / Immunofluorescence | 5 µg/mL (Human) |
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Polymerized porcine glucagon.
Reactivity Notes
The supplier lists reactivity with human, mouse, rabbit and rat. UniProt describes pro-glucagon as a secreted protein. Tissue expression noted by UniProt (rat): Glucagon is secreted in the A cells of the islets of Langerhans.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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