| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Glutathione peroxidase 1;GPx-1;GSHPx-1;1.11.1.9;Cellular glutathione peroxidase;GPX1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human GPX1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody is an antibody targeting GPX1. Common applications include WB, IHC, IP. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: IHO-7; isotype: Rabbit IgG; reactivity: Human,Mouse,Rat; observed MW: 22 kDa; calculated MW: 22088 MW.
Boster Bio Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody catalog # M01019-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Key elements and design rationale
- Target: GPX1 — Glutathione peroxidase 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: IHO-7; Isotype: Rabbit IgG
- Species reactivity: Human,Mouse,Rat
- Molecular weight guidance: Observed: 22 kDa; Calculated: 22088 MW
Biological background
Protein function (datasheet): Protects the hemoglobin in erythrocytes from oxidative breakdown.
Cellular localization (datasheet): Cytoplasm.
Tissue details (datasheet): Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. .
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Cancer Metabolism,Cell Biology,Metabolism,Mitochondrial,Mitochondrial Markers,Mitochondrial Metabolism,Oxidative Stress,Pathways and Processes,Redox Metabolism,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
