| Field | Specification |
|---|---|
| Target | |
| Alternative names | Glucocorticoid receptor;GR;Nuclear receptor subfamily 3 group C member 1;NR3C1;GRL; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human GR |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AOOE-14 is a rabbit monoclonal antibody that recognizes glucocorticoid receptor (gene NR3C1) in human, mouse and rat samples and is validated for Western blot and flow cytometry. The predicted molecular weight is 85.7 kDa, and the supplier reports an observed band at about 95 kDa.
The glucocorticoid receptor (GR, NR3C1) is a ligand-activated nuclear receptor for cortisol and synthetic glucocorticoids. On hormone binding it moves to the nucleus, binds glucocorticoid response elements and also restrains other transcription factors such as NF-κB and AP-1. GR mediates anti-inflammatory, metabolic and stress responses and is widely studied in endocrinology and immunology.
| Target | Glucocorticoid receptor (gene NR3C1; UniProt P04150, human) |
|---|---|
| Clone | AOOE-14 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 85.7 kDa |
| Observed MW | 95 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Flow cytometry | 1:20 |
Immunogen
Synthetic peptide based on the sequence of human GR.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. Tissue expression noted by UniProt (human): Widely expressed including bone, stomach, lung, liver, colon, breast, ovary, pancreas and kidney.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
