| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Somatotropin;Growth hormone;GH;GH-N;Growth hormone 1;Pituitary growth hormone;GH1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Immunogen | A synthesized peptide derived from human Growth Hormone |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Storage | |
| Target | |
| UniProt # |
Overview
This product is an anti-GH1 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone AADG-7; isotype Rabbit IgG; reactivity: Human. Reported application contexts include WB, IHC, IP (as provided in the source record). Boster Bio Anti-Growth Hormone GH1 Rabbit Monoclonal Antibody catalog # M00851-1. Tested in WB, IHC, IP applications. This antibody reacts with Human.
Key elements and design rationale
- Target: GH1 (Somatotropin).
- Antibody format: Monoclonal; clone AADG-7; isotype Rabbit IgG.
- Host: Rabbit.
- Species reactivity: Human (confirm in your model system with appropriate controls).
This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.
Biological background
GH1 (protein: Glycogen synthase kinase-3 beta (gsk3b)) is a commonly studied target in molecular and cellular biology. Functional context (as provided): Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Reported cellular localization context: Secreted. Tissue expression notes (as provided): KMT4 / Dot1L Antibody detects endogenous levels of total KMT4 / Dot1L
Research relevance and current trends
- Research context keywords from the source record include: Developmental Biology,Growth Factors/Hormones,Signal Transduction.
- Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
- Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.
Common research applications
- Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
- Immunohistochemistry (IHC): evaluate spatial distribution of target-positive staining in tissue architecture.
- Immunoprecipitation (IP): enrich target complexes for downstream immunoblot or interaction analyses.
Workflow ideas (metafield): Validate GH1 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect GH1 expression by Western blot in cell or tissue lysates, Detect GH1 in FFPE tissue sections by immunohistochemistry, Enrich GH1 by immunoprecipitation from lysates for downstream analysis
Notes for experimental interpretation
- Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
- Apparent molecular weight may vary by sample type and processing (observed MW: 22 kDa; calculated MW: 24847 MW).
- Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.
Additional product details (from the source record)
- Molecular weight (observed): 22 kDa
- Cellular localization (provided): Secreted.
- Tissue details (provided): KMT4 / Dot1L Antibody detects endogenous levels of total KMT4 / Dot1L
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
