| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Bcl2-associated agonist of cell death;BAD;Bcl-2-binding component 6;Bcl-2-like protein 8;Bcl2-L-8;Bcl-xL/Bcl-2-associated death promoter;Bcl2 antagonist of cell death;BAD;BBC6, BCL2L8; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human HLA DMB |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-HLA DMB Rabbit Monoclonal Antibody catalog # M03526. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Bcl2-associated agonist of cell death | Target: HLA-DMB | Function: Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. . | Research areas: Neurology Process,Neuroscience,Alzheimer's Disease,Neurodegenerative Disease
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 27H21 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human HLA DMB | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, ICC, FC
Observed MW: 29 kDa | Calculated MW: 18392 MW
Cellular localization: Mitochondrion outer membrane. Cytoplasm . Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. .
Tissue details: Expressed in a wide variety of tissues.
Status: Active
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