| Field | Specification |
|---|---|
| Target | |
| Alternative names | Insulin-like growth factor II;IGF-II;Somatomedin-A;T3M-11-derived growth factor;Insulin-like growth factor II;Insulin-like growth factor II Ala-25 Del;Preptin;IGF2;PP1446; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human IGF2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone IGE-9 is a rabbit monoclonal antibody that recognizes insulin-like growth factor 2 (gene IGF2) in human samples and is validated for Western blot and ICC/IF. The predicted molecular weight is 20.1 kDa, and the supplier reports an observed band at about 10 kDa.
Insulin-like growth factor 2 (IGF-2) is a growth-promoting peptide hormone that plays a major role in fetal and placental growth. The IGF2 gene is imprinted and mostly expressed from the paternal allele, and its dysregulation is linked to growth disorders such as Beckwith–Wiedemann and Silver–Russell syndromes.
| Target | Insulin-like growth factor 2 (gene IGF2; UniProt P01344, human) |
|---|---|
| Clone | IGE-9 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 20.1 kDa |
| Observed MW | 10 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Samples with a confirmed band (WB): human serum.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human IGF2.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes insulin-like growth factor 2 as a secreted protein. Tissue expression noted by UniProt (human): Expressed in heart, placenta, lung, liver, muscle, kidney, tongue, limb, eye and pancreas. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Tetsu Morioka et al. (2014) Non–Islet Cell Tumor-Induced Hypoglycemia Associated with Macronodular Pulmonary Metastases from Poorly Differentiated Thyroid Carcinoma. Thyroid. 10.1089/thy.2013.0141
