| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Insulin-like growth factor II;IGF-II;Somatomedin-A;T3M-11-derived growth factor;Insulin-like growth factor II;Insulin-like growth factor II Ala-25 Del;Preptin;IGF2;PP1446; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human IGF2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-IGF2/IGF II Rabbit Monoclonal Antibody is an antibody targeting IGF2. Common applications include WB, ICC, IF. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: IGE-9; isotype: Rabbit IgG; reactivity: Human; observed MW: 32 kDa; calculated MW: 20140 MW.
Boster Bio Anti-IGF2/IGF II Rabbit Monoclonal Antibody catalog # M00335. Tested in WB, ICC/IF applications. This antibody reacts with Human.
Key elements and design rationale
- Target: IGF2 — Insulin-like growth factor II
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: IGE-9; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 32 kDa; Calculated: 20140 MW
Biological background
Protein function (datasheet): The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
Cellular localization (datasheet): Secreted.
Tissue details (datasheet): Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Developmental Biology,Growth Factors,Growth Factors/Hormones,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunofluorescence / ICC: Visualize subcellular localization and co-localization patterns; consider fixation/permeabilization compatibility and controls.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
