| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Myoglobin;Mb; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | Purified human skeletal muscle myoglobin. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) is an antibody targeting MB. Common applications include IHC. Key specifications include host: Mouse; clonality: Monoclonal; clone: Clone: MG-1; isotype: Mouse IgG1; reactivity: Human; observed MW: 200 kDa; calculated MW: 17157 MW.
Boster Bio Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) catalog # MA1062. Tested in IHC applications. This antibody reacts with Human.
Key elements and design rationale
- Target: MB — Myoglobin
- Antibody format: Host: Mouse; Clonality: Monoclonal; Clone: Clone: MG-1; Isotype: Mouse IgG1
- Species reactivity: Human
- Molecular weight guidance: Observed: 200 kDa; Calculated: 17157 MW
Specificity note: No cross reactivity with other proteins.
Biological background
Protein function (datasheet): Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Scientific background (datasheet): Human myoglobin has 152 residues. Two myoglobin variants were found. The myoglobin locus mapped to 22q11-22q13. The myoglobin gene is about 10.5 kb long and contains two introns as in the case with hemoglobin genes. Myoglobin may serve a variety of functions in muscular oxygen supply, such as O (2) storage, facilitated O (2) diffusion, and myoglobin-mediated oxidative phosphorylation.
Cellular localization (datasheet): Secreted .
Tissue details (datasheet): Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. .
Sequence similarities (datasheet): Belongs to the globin family.
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Cardiovascular,Energy Metabolism,Energy Transfer Pathways,Metabolic Signaling Pathways,Metabolism,Oxidative Stress,Pathways and Processes,Redox Metabolism,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Cross-reactivity (datasheet): No cross-reactivity with other proteins
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
