| Field | Specification |
|---|---|
| Target | |
| Alternative names | Glutamate receptor ionotropic, NMDA 1;GluN1;Glutamate [NMDA] receptor subunit zeta-1;N-methyl-D-aspartate receptor subunit NR1;NMD-R1;GRIN1;NMDAR1; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human NMDAR1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AAHF-7 is a rabbit monoclonal antibody that recognizes glutamate receptor ionotropic, NMDA 1 (gene GRIN1) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 105.4 kDa, and the supplier reports an observed band at about 120 kDa.
GluN1 (GRIN1) is the obligatory subunit of NMDA receptors, the glutamate-gated channels that allow Ca2+ entry. It binds the co-agonist glycine or D-serine, and receptor opening also requires glutamate on GluN2 plus depolarization to relieve Mg2+ block, making it central to synaptic plasticity, learning and memory.
| Target | Glutamate receptor ionotropic, NMDA 1 (gene GRIN1; UniProt Q05586, human) |
|---|---|
| Clone | AAHF-7 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 105.4 kDa |
| Observed MW | 120 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human NMDAR1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places glutamate receptor ionotropic, NMDA 1 in the cell membrane, postsynaptic cell membrane, postsynaptic density membrane and synaptic cell membrane.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
